Quo Vadis Structural Biology?

quo_vadis.jpg The first ever ‘Quo Vadis Structural Biology?’ Symposium will take place on May 5th and 6th 2008 in Boston, Massachusetts. Throughout this interactive, 2-day symposium, speakers from Harvard University and outside will present their work, plus 2 tracks of hands-on workshops focused on structural biology computing will be offered. The first track focuses on tools and techniques for using structural biology software. The second track is more general and focuses on building the tools and computing infrastructure to support your own research needs.

Quo Vadis is a latin phrase that roughly translates to “where are you headed?” This summit is designed to give its attendees an extensive array of opportunities to discuss and learn about the future of structural biology, with an emphasis on computation.

  • Monday, May 5th 2008, 9am-8pm
  • Tuesday May 6th, 9am-5pm
  • For further assistance e-mail:quovadis@sbgrid.org

Two-workshop track is sold out.

Post-conference website

One workshop track

Lecture Session 1: Quo Vadis Structural Biology?
Monday, 1-8PM, The Conference Center at Harvard Medical - Amphitheater
1:00-1:10 Stephen C Harrison Opening Remarks
1:10-2:00 David E Shaw Toward Millisecond-Scale Molecular Dynamics Simulations of Proteins.
2:00-2:30 James Chou Membrane Protein Structure Determination by NMR
2:30-3:15 Joachim Frank Structure Determination Using Single-Particle Reconstruction
3:15-3:30 Apple Break
3:30-3:55 Miron Livny Open Science Grid
3:55-4:40 Axel Brunger X-ray structure determination at low resolution
4:40-5:00 Gaël McGill Visualizing Cell and Molecular Processes
5:00-5:15 Piotr Sliz Scientific Software Award Presentation
5:15-6:00 Leemor Joshua-Tor NADP Regulates the Yeast GAL Induction System – a new twist to an old story
6:00-7:00 Buffet Dinner
7:00-8:00 Mark Gerstein Protein Structures and Networks
Tuesday 9-1 PM; Workshop Session O
Animating your Data (4) or
Introduction to the Mac OS X Development and Application Tools (5) or Advances in Structure-based Lead Discovery and Optimization (2) or
Introductory Python Programming for Biologists (6)

Structural Biology Track (SOLD OUT)

Monday 9-1 PM; Workshop Session A (lunch included)
Advanced Crystallography (1) or
Advances in Structure-based Lead Discovery and Optimization (2) or
Introduction to the Mac OS X Development and Application Tools (5) or
Introductory Python Programming for Biologists (6)
Lecture Session 1: Quo Vadis Structural Biology?
Monday, 1-8PM, The Conference Center at Harvard Medical - Amphitheater
1:00-1:10 Stephen C Harrison Opening Remarks
1:10-2:00 David E Shaw Toward Millisecond-Scale Molecular Dynamics Simulations of Proteins.
2:00-2:30 James Chou Membrane Protein Structure Determination by NMR
2:30-3:15 Joachim Frank Structure Determination Using Single-Particle Reconstruction
3:15-3:30 Apple Break
3:30-3:55 Miron Livny Open Science Grid
3:55-4:40 Axel Brunger X-ray structure determination at low resolution
4:40-5:00 Gaël McGill Visualizing Cell and Molecular Processes
5:00-5:15 Piotr Sliz Scientific Software Award Presentation
5:15-6:00 Leemor Joshua-Tor NADP Regulates the Yeast GAL Induction System – a new twist to an old story
6:00-7:00 Buffet Dinner
7:00-8:00 Mark Gerstein Protein Structures and Networks
Lecture Session 2: Software Showcase Session
Tuesday, 9-1PM, HIM (lunch included)
9:00-9:45 Frank Delaglio Applications of NMR in SB and Drug Discovery
9:45-10:30 Harry Powell Data Processing with iMosflm
10:30-11:15 Ralf Grosse-Kunstleve Automated Structure Determination with Phenix
11:15-12:00 Nikolaus Grigorieff High-resolution refinement of EM structures with Frealign
Lecture Session 3: Programming for Biologists
Tuesday, 1-2PM, HIM
1:00-2:00 Paul Emsley Programming for Biologists
Tuesday 2-5 PM; Workshop Session B
Roadmaps for Structure Determination (3) or
Animating your Data (4) or
Introduction to the Mac OS X Development and Application Tools (5) or
Introductory Python Programming for Biologists (6)

Workshops

  1. Advanced Crystallography (A)
    • Non standard crystallization techniques for screening and optimization: Naomi Chayen
    • Computing and programming with CCP4: Harry Powell
    • Low resolution refinement: Piotr Sliz
    • Low resolution model-building with coot and other tools: Paul Emsley
  2. Advances in Structure-based Lead Discovery and Optimization (A and O): Woody Sherman
    • Overview of the Schrödinger software suite
    • Scientific advances in docking and scoring; Accounting for receptor flexibility in docking and scoring
    • Scripting and automation with Python and KNIME; Benefits of using PrimeX to refine crystal structures
  3. Roadmaps for structure determination (B)
  4. Animating your data: tools from Hollywood (B and O): Gaël McGill
    • An introduction to the capabilities and uses of Maya in biological visualization
    • A hands-on exploration of the Maya user interface and basic toolset
    • A tutorial during which participants will create a simple molecular animation
  5. Introduction to the Mac OS X Development and Application Tools (A and B): David Gohara
    • Introduction to the Apple developer tools and Xcode IDE
    • Overview of scientifically useful Apple technologies
    • Real-world examples of Apple technologies for scientific computing
  6. Introductory Python Programming for Biologists (A and B): Ian Stokes-Rees and Ralf Grosse-Kunstleve
    • Why scientists love programming in Python?
    • A short tour of syntax, structures, and features; Creating and using scripts, modules, and packages
    • Scientific computing in Python, demos and user exercises
  7. Designing and maintaining a structural biology computing lab (S): Ian Levesque and Ben Eisenbraun
    • SBGrid workstation primer
    • Networking and securing your lab
    • SBGrid software and grid integration

Schedule and Registration options

Monday May 5th, 2008

  • 9-12PM: Workshops from group A (pick one)
  • 9-12PM: Workshop S, part 1.
  • 12-1PM: Lunch for workshop participants
  • 1-8PM: Session 1: Quo Vadis Structural Biology? (dinner 6-7PM)

Tuesday May 6th, 2008

  • 9-12PM: Session 2: Software Showcase Session
  • 9-12PM (concurrent): Workshops from group O
  • 12-1PM: Lunch
  • 1-2PM: Session 3: Programming for Biologists
  • 2-5PM: Workshops from group B
  • 2-5PM: Workshop S - part 2.

Registration Options:

  • Structural Biologists: Sessions 1, 2 and 3, one workshop from group A and one workshop from group B.
  • Others: Session 1 and one workshop from group O.
  • Quo Vadis Only: Session 1.
  • System Administrators: Sessions 1,2 and 3 and two-day workshop S.

Cancellation and Refund Policy

  • Cancellations received at least 30 days prior to meeting date: You will receive all amounts paid to Harvard Medical School minus a $30 handling fee. You will also forfeit the $25 per workshop fee (if applicable). Refunds will only be issued to the original form of payment or by check. You must e-mail, your registration cancellation request to quovadis at sbgrid.org. Registration refunds will be processed within 30 days.
  • Cancellations received less than 30 days prior to meeting date: You will receive no refund from Harvard Medical School. Refunds will not be issued to no-show registrants. Materials will be sent to no-show registrants upon request.
  • Substitution of another individual for an established registrant will be accepted up to the first morning of the conference; just write to quovadis at sbgrid.org with the details.
  • If any workshop of the program is canceled by the SBGrid, you will be offered an option to transfer to another workshop or refunded up to $100 per event.

Organizers:

Sponsors: